Patient history & diagnosis:
subject is a 35-year old male suffering from a symptomatic medial left knee OA for 10 months; XR showed moderate malalignement, 10° varus; NMR showed a III/IV degree chondral lesion on the medial femoral condyle.
Diagnostic arthroscopy:
a joint inspection was performed via arthroscopy in order to confirm the NMR diagnosis.
Bone Marrow Aspirate harvesting:
bone marrow aspiration was performed from the posterior iliac crest during the same surgical session of HYALOFAST® implantation. The harvested bone marrow was processed for concentration directly in the operating room by using a proper special centrifuge and disposable double chamber devices.
Chondral lesion preparation:
the knee joint was opened using a standard minimal invasive approach aimed at the lesion site; the chondral lesion was then carefully debrided removing unstable cartilage until a stable shoulder and a well-contained defect was achieved.
HYALOFAST shaping and arthrotomic application:
defect size was assessed by a sterile template and the imprint was cut and transferred onto the HYALOFAST® pad;
HYALOFAST® was cut to fit the lesion shape; bone marrow concentrate was loaded onto the shaped HYALOFAST® pad and, due to its hydrophilic properties, the scaffold allowed an homogeneous distribution of the concentrate fluid rapidly;
eventually the HYALOFAST® patch correctly sized was gently applied on the lesion bed with sterile forceps.